82-5 E-mail: This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License () which permits unrestricted non-commercial use, distri- bution, and reproduction in any medium, provided the original work is properly cited.Ĭopyrights © 2018 The Korean Society of Radiology 371 Index terms Pulmonary Disease, Chronic Obstructive Emphysema Multidetector Computed Tomography Respiratory Muscles Diaphragm Received SeptemRevised NovemAccepted Febru* Corresponding author: Ki-Nam Lee, MD Department of Radiology, Dong-A University Hospital, 26 Daesingongwon-ro, Seo-gu, Busan 49201, Korea. Conclusion: The CT measurement of the patient’s respiratory muscles may reflect clinical and visual severity in the patients with emphysema. As noted, both the VAE and PFT values were mostly contributed by the CSA and attenuation of ser- ratus anterior and attenuation of diaphragm crus among all respiratory muscles. The CSA and the attenuation of respiratory mus- cles remained significant for its relation for the VAE and PFT values.
Results: The CSA of the pectoralis major ( p = 0.002) and subsequently the serratus anterior ( p = 0.011) were found to be lower in patients with emphysema than as com- pared to those in the control group. The multiple linear regression analysis of each CT measurement on the VAE and PFT values was used to determine the most affective parameters among the recorded and identified CT measurements. The correlation between the CT measurements with visual assessment of emphysema (VAE), and the PFT values were completed and recorded. The clinical severity for the patients was determined by the value of the actual forced expiratory volume in 1 second/forced vital capacity at the pulmo- nary function test (PFT). Materials and Methods: The cross sectional area (CSA) and attenuation of respira- tory muscles in the patients with emphysema ( n = 71) were subsequently retrospec- tively reviewed. To improve practical ap- plicability we used visual assessment of emphysema at standard Quantitative Computed Tomography Assessment of Respiratory Muscles in Male Patients Diagnosed with Emphysema 폐기종 환자에서 호흡 근육의 양적 CT 평가 Ji-Yeon Han, MD 1, Ki-Nam Lee, MD 2 *, Eun-Ju Kang, MD 2, Jin Wook Baek, MD 3 1 Department of Radiology, Dongnam Institute of Radiological & Medical Sciences, Busan, Korea 2 Department of Radiology, Dong-A University Hospital, Busan, Korea 3 Department of Radiology, Inje University College of Medicine, Busan Paik Hospital, Busan, Korea Purpose: The aim of this study was to accurately evaluate the significance and cor- relation between the clinical severity and the morphologic feature of respiratory muscles in patients with emphysema as noted using computed tomography (CT).
Visual assessment of emphysema by using standard CT image was proven to be simple and reliable. CT emphysema or ventilation quantification has already demonstrated a good correlation with clinical severity (11, 12). Although these investigations provided compelling data for functional correlation of each respiratory muscle, they limited to analyze one or two respiratory muscles at a time. With arising interest on functional impair- ment of COPD, a few recent studies focused on showing clinical correlation of the cross sectional areas of pectoralis muscle, in- tercostals and latissimus dorsi muscle (9, 10) visualized at chest CT in COPD patients. A few studies in particular measured the apposition length of diaphragm at the costal insertion either indirectly by a chest ra- diograph or by spiral computed tomography (CT) in the pa- tients with COPD. Research on respiratory muscles in patients with COPD and physiopathological effects on their performances basis has been performed in the past, but they have shown no gross morphologic changes of the muscles (1-8). Copyrights © 2018 The Korean Society of Radiology 371 Original Article pISSN 1738-2637 / eISSN 2288-2928 J Korean Soc Radiol 2018 78(6):371-379 INTRODUCTION Respiratory muscles in the patients with chronic obstructive pulmonary disease (COPD) are affected structurally and physi- ologically in complex way.
0 kommentar(er)
